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Anoctamin 2 identified as an autoimmune target in - PNAS

Key Applications: Immunocytochemistry; Immunohistochemistry; Immunohistochemistry (Paraffin) Application Notes: Immunohistochemistry(paraffin): Results: GFAP-antibody was found in active period sera of 2 IIH patients with classical symptoms and good treatment response. Two remission period sera obtained at different time points from one of these cases showed lower titers of GFAP-antibody positivity. IgG from positive samples yielded an astrocytic immunoreactivity pattern. Se hela listan på radiopaedia.org GFAp antibodies Indication Investigation on suspicion of autoimmune CNS-disease s . Method C ell-based assay (CBA); indirect immunofluorescence on GFAp transfected cells. The method is not yet validated.

Cat.No. 16825-1-AP. KD/KO Validated. GFAP.

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R-PLEX Human GFAP Antibody Set The R-PLEX platform offers matched sets of antibodies and calibrators for a wide menu of biomarkers. The R-PLEX Human GFAP Antibody Set can be used with other MSD components (see "Recommended Components" tab below) to build assays that measure GFAP. • GFAP_HUMAN antibody • gfapl antibody • Glial fibrillary acidic protein antibody • Intermediate filament protein antibody • wu:fk42c12 antibody • xx:af506734 antibody • zgc:110485 antibody. Storage.

Anoctamin 2 identified as an autoimmune target in - PNAS

av L Li · 2006 — brain ischemia and neurotrauma by using a mouse model in which the GFAP and vimentin Visualization of astrocytes with antibodies against GFAP. GFAP antibody, Cell signaling, 3670. GAP43 antibody, Transduction laboratories, 612262. BDNF antibody, Millipore, AB1534SP. HLA-DQB1*05:01 [293] · HLA-DRB1*10:01 HLA-DRB1*10:01 [292] · C1 inhibitor function C1 inhibitor funktion [926] · GFAp antibodies GFAp-antikroppar [996] av J Schuck · 2000 · Citerat av 32 — The GFAP‐antibody was also used in immunoelectron microscopy (1:50).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFAP antibody [EPR1034Y] (ab68428) IHC image of GFAP staining in a formalin fixed, paraffin embedded normal human hippocampus tissue section, performed on a Leica Bond™ system using the standard protocol F. Flow cytometric analysis of HeLa cells (blue) and SNB-19 cells (green) using GFAP (GA5) Mouse mAb (solid lines) or a concentration-matched Mouse (G3A1) mAb IgG1 Isotype Control #5415 (dashed lines). Anti-mouse IgG (H+L), F (ab') 2 Fragment (Alexa Fluor® 488 Conjugate) #4408 was used as a secondary antibody. Monoclonal mouse antibody provided in liquid form as cell culture supernatant dialysed against 0.05 mol/L Tris-HCl, pH 7.2, and containing 15 mmol/L NaN 3. Solutions: Concentrate; Species: Mouse Anti-Human; Specificity: As demonstrated by immunocytochemistry, the antibody labels GFAP in astrocytes and cells of astrocytic origin (1, 2). Glial fibrillary acidic protein (GFAP) is a 50 kDa intracytoplasmic filamentous protein that constitutes a portion of the cytoskeleton in astrocytes. With increasing astrocyte malignancy, there is a progressive loss of GFAP production. This antibody is a useful aid for the classification of astrocytoma and glioblastoma.
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Excellent Glial, Astrocyte Marker. Widely used and referenced in customer publications. This GFAP works for immunohistochemistry and western blotting. IHC staining of purified anti-GFAP antibody (clone SMI 23) on formalin-fixed paraffin-embedded mouse brain tissue.

Cross-reactivity with GFAP-R416W and other GFAP mutant proteins can be expected.
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Så kommer neurofilament i serum att användas

The R-PLEX Human GFAP Antibody Set can be used with other MSD components (see "Recommended Components" tab below) to build assays that measure GFAP. • GFAP_HUMAN antibody • gfapl antibody • Glial fibrillary acidic protein antibody • Intermediate filament protein antibody • wu:fk42c12 antibody • xx:af506734 antibody • zgc:110485 antibody. Storage. 100 µl total IgY fraction in PBS + 10 mM NaN3. Adequate amount of material to conduct 10-mini Western Blots. GFAP (Glial Fibrillary Acidic Protein) is a Protein Coding gene. Diseases associated with GFAP include Alexander Disease and Central Neurocytoma.